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There are several matches for 'bmp family protein'.
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1167 matches
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organism
protein
1)
Homo sapiens
BMP2K -
BMP
-2-inducible
protein
kinase; May be involved in osteoblast differentiation; Belongs to the
protein
kinase superfamily. Ser/Thr
protein
kinase
family
.
[a.k.a. HPA026436, XM_005263117.1, ENSG00000138756]
2)
Homo sapiens
SMAD1 - Mothers against decapentaplegic homolog 1; Transcriptional modulator activated by
BMP
(bone morphogenetic
proteins
) type 1 receptor kinase. SMAD1 is a receptor- regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic
protein
(
BMP
)- mediated cardiac-specific gene expression. Belongs to the dwarfin/SMAD
family
.
[a.k.a. 3Q47, NP_001341745, 4086]
3)
Homo sapiens
ZNF8 - Zinc finger
protein
8; Transcriptional repressor. May modulate
BMP
and TGF-beta signal transduction, through its interaction with SMAD
proteins
. Belongs to the krueppel C2H2-type zinc-finger
protein
family
.
[a.k.a. 7554, HGNC:13154, HPA034797]
4)
Homo sapiens
RGMB - RGM domain
family
member B; Member of the repulsive guidance molecule (RGM)
family
that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic
protein
(
BMP
) coreceptor that potentiates
BMP
signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.
[a.k.a. NM_001012761.2, Q6NW40, RGM domain family member B]
5)
Homo sapiens
HJV - Hemojuvelin; Acts as a bone morphogenetic
protein
(
BMP
) coreceptor. Through enhancement of
BMP
signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis. Belongs to the repulsive guidance molecule (RGM)
family
.
[a.k.a. ENSP00000411863, ENSP00000489347, HJV-202]
6)
Homo sapiens
SMAD9 - Mothers against decapentaplegic homolog 9; Transcriptional modulator activated by
BMP
(bone morphogenetic
proteins
) type 1 receptor kinase. SMAD9 is a receptor- regulated SMAD (R-SMAD); Belongs to the dwarfin/SMAD
family
.
[a.k.a. AAI04763.1, EAX08571.1, Mothers against decapentaplegic homolog 9]
7)
Homo sapiens
ZNF521 - Zinc finger
protein
521; Transcription factor that can both act as an activator or a repressor depending on the context. Involved in
BMP
signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of
BMP
target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes; Belongs to the krueppel C2H2-type zinc-finger
protein
family
.
[a.k.a. LYST-interacting protein 3, ENST00000582584.1, ENST00000580488]
8)
Homo sapiens
SMURF1 - E3 ubiquitin-
protein
ligase SMURF1; E3 ubiquitin-
protein
ligase that acts as a negative regulator of
BMP
signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the
BMP
pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF
family
members and RHOA. Promotes ubiquitination and subsequent proteasomal degradation of MAVS. Plays a role in dendrite formation by melanocytes.
[a.k.a. R-HSA-170834, uc003upu.3, AF199364]
9)
Homo sapiens
ECSIT - Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter
protein
of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the
BMP
signaling pathway. Required for normal embryonic development (By similarity); Belongs to the ECSIT
family
.
[a.k.a. ECSIT homolog (Drosophila), K7ESM8, 51295]
10)
Homo sapiens
RNF165 - E3 ubiquitin-
protein
ligase RNF165; E3 ubiquitin-
protein
ligase that acts as a regulator of motor axon elongation. Required for efficient motor axon extension in the dorsal forelimb by enhancing the transcriptional responses of the SMAD1/SMAD5/SMAD8 effectors, which are activated downstream of
BMP
. Acts by mediating ubiquitination and degradation of SMAD inhibitors such as SMAD6, SMAD7, SKI and SNON isoform of SKIL. Belongs to the Arkadia
family
.
[a.k.a. CCDS32823, 5ULK, ENSP00000269439]
11)
Mus musculus
Fam83g -
Protein
FAM83G; May regulate the bone morphogenetic
proteins
(
BMP
) pathway. Belongs to the FAM83
family
.
[a.k.a. AL596209, ENSMUST00000093019.5, 69640]
12)
Mus musculus
Rgmb - RGM domain
family
member B; Member of the repulsive guidance molecule (RGM)
family
that contributes to the patterning of the developing nervous system. Acts as a bone morphogenetic
protein
(
BMP
) coreceptor that potentiates
BMP
signaling. Promotes neuronal adhesion. May inhibit neurite outgrowth (By similarity).
[a.k.a. RGM domain family member B, Q7TQ33, Rgmb-201]
13)
Mus musculus
Nog - Noggin; Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogenetic
proteins
(
BMP
) signaling which is required for growth and patterning of the neural tube and somite. Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (By similarity). Belongs to the noggin
family
.
[a.k.a. 18121, uc007kwh.2, AAI32528.1]
14)
Mus musculus
Smad5 - Mothers against decapentaplegic homolog 5; Transcriptional modulator activated by
BMP
(bone morphogenetic
proteins
) type 1 receptor kinase. SMAD5 is a receptor- regulated SMAD (R-SMAD) (By similarity). Required for angiogenesis. Belongs to the dwarfin/SMAD
family
.
[a.k.a. SMAD 5, 17129, XM_006517117.1]
15)
Mus musculus
Smad9 - Mothers against decapentaplegic homolog 9; Transcriptional modulator activated by
BMP
(bone morphogenetic
proteins
) type 1 receptor kinase. SMAD9 is a receptor- regulated SMAD (R-SMAD). Has been shown to be activated by activin type I receptor-like kinases (ALK-2, ALK-3, ALK-6) which stimulate heteromerization between SMAD9 and SMAD4. May play a role in osteoblast differentiation and maturation; Belongs to the dwarfin/SMAD
family
.
[a.k.a. Mothers against decapentaplegic homolog 9, NM_019483.5, MAD homolog 9]
16)
Mus musculus
Smurf1 - E3 ubiquitin-
protein
ligase SMURF1; E3 ubiquitin-
protein
ligase that acts as a negative regulator of
BMP
signaling pathway (By similarity). Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the
BMP
pathway (By similarity). Promotes ubiquitination and subsequent proteasomal degradation of TRAF
family
members and RHOA (By similarity). Promotes ubiquitination and subsequent proteasomal degradation of MAVS. Plays a role in dendrite formation by melanocytes (By similarity).
[a.k.a. R-MMU-1280218, XM_011241016, E9PYU8]
17)
Mus musculus
Ecsit - Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter
protein
of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the
BMP
signaling pathway. Required for normal embryonic development. Belongs to the ECSIT
family
.
[a.k.a. R-MMU-166058, R-MMU-975871, ENSMUSP00000136247]
18)
Mus musculus
Rnf165 - E3 ubiquitin-
protein
ligase RNF165; E3 ubiquitin-
protein
ligase that acts as a regulator of motor axon elongation. Required for efficient motor axon extension in the dorsal forelimb by enhancing the transcriptional responses of the SMAD1/SMAD5/SMAD8 effectors, which are activated downstream of
BMP
. Acts by mediating ubiquitination and degradation of SMAD inhibitors such as SMAD6, SMAD7, SKI and SNON isoform of SKIL ; Belongs to the Arkadia
family
.
[a.k.a. AK133955, ENSMUST00000026494, Ring finger protein 165]
19)
Drosophila melanogaster
cv-d - Crossveinless d (cv-d) encodes the sole Drosophila member of an insect vitellogenin-like lipoprotein
family
. It can bind lipids and members of the
BMP
protein
family
. Loss of cv-d produces viable flies with disrupted
BMP
signaling in the developing wing.
[a.k.a. FBgn0265048, cv-d-PA, FBpp0082643]
20)
Drosophila melanogaster
tkv - Receptor
protein
serine/threonine kinase; Thickveins (tkv) encodes a transforming growth factor beta type I receptor. Together with the product of put, it functions as a receptor of the product of dpp and therefore contributes to the
BMP
signaling pathway; Belongs to the
protein
kinase superfamily. TKL Ser/Thr
protein
kinase
family
. TGFB receptor subfamily.
[a.k.a. FBgn0003716, tkv-PA, tkv-PD]
1167 matches
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